Center for Inherited Disease Research (CIDR) High Throughput Sequencing and Genotyping Resource Access (X01) | PAR 17 269

Opportunity Information: Apply for PAR 17 269

The Center for Inherited Disease Research (CIDR) High Throughput Sequencing and Genotyping Resource Access (X01) opportunity (PAR-17-269) is a National Institutes of Health (NIH) grant mechanism designed to give researchers access to large-scale genomic services rather than primarily providing direct research dollars. Through this program, investigators can use CIDR as a centralized, high-capacity resource for high-throughput genotyping, next-generation sequencing, and related statistical genetics support. The overall purpose is to speed up gene discovery and the identification of genetic variants that influence human health and disease, especially in studies where generating high-quality genomic data at scale would be difficult, inefficient, or too costly for individual investigator laboratories to perform on their own.

A key emphasis of this opportunity is leveraging well-phenotyped sample collections. In practical terms, it supports projects that already have strong clinical, epidemiological, or other phenotype data and now need genotype or sequencing data added to those specimens to enable powerful genetic analyses. CIDR is positioned as a specialized laboratory that focuses on genomic services that are not easily replicated in smaller settings, offering current, high-throughput platforms and technical expertise along with supporting analytic and statistical genetics services. The program is NIH-wide but managed by the National Human Genome Research Institute (NHGRI), meaning it is intended to serve a broad range of NIH-funded and NIH-relevant biomedical research areas, not just a single disease category.

CIDR’s role is to provide “state-of-the-art” capability and consistency, which can be particularly important for large consortium efforts, multi-site studies, or projects where data comparability and standardized processing pipelines matter. By centralizing genotyping/sequencing and pairing it with statistical genetics support, the resource is meant to reduce duplication of effort across labs, improve quality control, and help research teams move more quickly from specimens to analyzable genomic datasets. Details on the specific platforms and services available are maintained by CIDR and are referenced in the announcement through the CIDR website (http://www.cidr.jhmi.edu), which is where applicants would typically confirm current technologies, sample requirements, and service offerings.

Eligibility for this opportunity is broad and includes many types of U.S. organizations that commonly apply for NIH opportunities, such as state, county, city, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; nonprofit organizations (with or without 501(c)(3) status); for-profit organizations (other than small businesses) and small businesses; public housing authorities/Indian housing authorities; and Native American tribal governments (federally recognized) as well as other Native American tribal organizations. In addition, the opportunity explicitly highlights a range of other eligible applicants, including Alaska Native and Native Hawaiian Serving Institutions; Asian American, Native American, and Pacific Islander Serving Institutions (AANAPISIs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs); faith-based or community-based organizations; eligible federal agencies; regional organizations; U.S. territories or possessions; and even non-domestic (non-U.S.) entities (foreign organizations). This wide eligibility reflects the NIH-wide scope and the idea that many different types of research organizations may have valuable cohorts or specimen collections that could benefit from high-throughput genomic data generation.

From the source details provided, the opportunity is categorized as discretionary, uses a grant funding instrument, and falls under the health funding activity category (CFDA 93.172). The opportunity was created on 2017-05-03, and the listed original closing date was 2020-06-11. The announcement text does not specify an award ceiling or expected number of awards in the provided extract, which is consistent with resource-access style programs where the “award” may be better understood as approved access to a service pipeline and associated capacity rather than a standard budgeted grant amount. For applicants, the practical takeaway is that this mechanism is aimed at enabling large-scale genotyping and sequencing (plus statistical genetics support) through a centralized NIH-supported resource, especially for projects that can make strong use of existing phenotype-rich samples and that would benefit from CIDR’s throughput, platform currency, and specialized expertise.

• The National Institutes of Health in the health sector is offering a public funding opportunity titled "Center for Inherited Disease Research (CIDR) High Throughput Sequencing and Genotyping Resource Access (X01)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.172.
• This funding opportunity was created on 2017-05-03.
• Applicants must submit their applications by 2020-06-11. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

Apply for PAR 17 269

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