NIA Program Project Applications (P01 Clinical Trial Optional) | PAR 19 314

Opportunity Information: Apply for PAR 19 314

The National Institute on Aging (NIA), part of the National Institutes of Health, is soliciting investigator-initiated Program Project Grant (P01) applications under the funding opportunity titled "NIA Program Project Applications (P01 Clinical Trial Optional)" (Funding Opportunity Number PAR 19 314). This is a discretionary grant opportunity in the health category (CFDA 93.866) designed to support larger, coordinated research efforts that align with NIA's mission areas related to aging. The "clinical trial optional" wording signals that applicants may propose studies that include clinical trials when appropriate, but a clinical trial is not required for submission.

A defining feature of this P01 opportunity is the expectation that each application will be organized around a single, well-justified central theme, focus, and overall objective, and that it will integrate multiple projects in a way that creates added value beyond what separate, stand-alone grants would accomplish. Specifically, every application must include at least three scientifically related research projects that are clearly connected to the shared theme. In addition to those research projects, the application must include an Administrative Core, which is responsible for leadership, coordination, and overall management of the program project. In practice, this means the proposed work should demonstrate strong scientific cohesion, meaningful collaboration across projects, and a management plan that can keep the multi-project structure functioning smoothly and productively.

The eligibility rules are broad and include many types of U.S.-based organizations and governmental entities. Eligible applicants include state, county, city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; Native American tribal governments (federally recognized); public housing authorities and Indian housing authorities; Native American tribal organizations that are not federally recognized tribal governments; nonprofits with or without 501(c)(3) IRS status (other than institutions of higher education); for-profit organizations other than small businesses; and small businesses. The opportunity also explicitly calls out additional eligible applicant categories such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, eligible federal agencies, Indian/Native American Tribal Governments (other than federally recognized), and U.S. territories or possessions.

At the same time, the opportunity places clear limits on foreign participation. Non-domestic (non-U.S.) entities (foreign institutions) are not eligible to apply as the applicant organization, and non-domestic components of U.S. organizations are also not eligible to apply as components. However, foreign components are allowed when they meet the NIH definition of a foreign component as described in the NIH Grants Policy Statement, meaning U.S. applicant organizations can include certain well-justified international elements within the overall project when permitted and properly documented.

From the administrative details provided, this funding opportunity was created on 2019-07-11, and the original closing date listed is 2022-05-25. No award ceiling amount or expected number of awards is specified in the source data provided, which often means applicants need to rely on NIH and NIA budget guidance for P01 mechanisms and craft budgets that are appropriate to the scope and justified by the proposed multi-project activities. Overall, the opportunity is aimed at teams capable of designing an integrated, multi-project research program in aging, supported by strong central leadership through an Administrative Core and a set of at least three interrelated projects that collectively advance a coherent scientific agenda.

• The National Institutes of Health in the health sector is offering a public funding opportunity titled "NIA Program Project Applications (P01 Clinical Trial Optional)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.866.
• This funding opportunity was created on 2019-07-11.
• Applicants must submit their applications by 2022-05-25. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

Apply for PAR 19 314

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