Opportunity Information: Apply for PAR 16 376
The grant opportunity titled "T2 Translational Research on Aging: Small Business Innovation Awards (R43/R44)" (Funding Opportunity Number PAR-16-376) is a National Institutes of Health (NIH) Small Business Innovation Research (SBIR) program announcement designed to move aging-related scientific advances closer to real-world use. Its core purpose is to encourage small businesses to take promising research findings and translate them into practical, market-ready solutions that can improve the health, day-to-day function, and independence of older adults. The emphasis is not only on scientific or technical innovation, but also on creating something that has a realistic pathway to commercialization and broad benefit for aging populations.
This FOA supports translational aging research, meaning projects are expected to be oriented toward development and implementation rather than basic discovery alone. The types of outputs envisioned include novel devices, products, healthcare practices, intervention programs, and related technologies or services that can be adopted in clinical, community, home-based, or other care settings relevant to older adults. In other words, the program is interested in work that bridges the gap between research and usable tools, with clear potential to become a commercial offering and to meaningfully improve outcomes tied to aging, such as functional capacity, quality of life, and the ability to live independently.
The funding mechanism uses the SBIR R43/R44 grant structure, which generally aligns with phased innovation funding commonly used in U.S. small business R&D. While the source text does not spell out the phase details, the R43/R44 framework typically corresponds to early-stage feasibility and development work moving toward more advanced R&D and commercialization readiness. The announcement makes clear that the intended applicants are small businesses, and the eligible applicant category listed is "Small businesses." The funding instrument is a grant, the activity category is health, and the associated CFDA number is 93.866, which relates to NIH aging research programs.
Eligibility is primarily limited to U.S. small business concerns consistent with SBIR requirements. Foreign institutions (non-U.S. entities) are explicitly not eligible to apply, and non-U.S. components of U.S. organizations are also not eligible to apply. However, the FOA notes that "foreign components" may be allowed as defined by the NIH Grants Policy Statement, which typically means a U.S. applicant might be able to include certain discrete elements of the project conducted abroad if NIH policy criteria are met and the FOA permits it. The practical takeaway is that the applicant organization must be a U.S. small business, and any international involvement would need to be carefully justified and structured under NIH rules rather than treated as a standard foreign collaboration led by a non-U.S. entity.
Administratively, the opportunity is offered by the National Institutes of Health and was created on 2016-07-22, with an original closing date listed as 2018-01-24. The listing does not provide an award ceiling or the expected number of awards in the provided fields, so those specifics would require consulting the full FOA text. Overall, the program is aimed at accelerating the translation of aging research into commercially viable innovations that can tangibly help older adults maintain health and independence, using the SBIR pathway to leverage private-sector development and market deployment.Apply for PAR 16 376
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "T2 Translational Research on Aging: Small Business Innovation Awards (R43/R44)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.866.
- This funding opportunity was created on 2016-07-22.
- Applicants must submit their applications by 2018-01-24. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Small businesses.
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