Opportunity Information: Apply for PA 18 792
The Advancing Evidence into Practice through Shared, Interoperable Clinical Decision Support Resources (U18) funding opportunity (PA 18-792) is a discretionary grant program from the Agency for Health Care Research and Quality (AHRQ) designed to speed up the real-world adoption of proven clinical evidence by improving how clinical decision support (CDS) is created, shared, and implemented across health care settings. The core idea is to fund innovative research projects that take evidence (for example, guidelines, best practices, and validated clinical knowledge) and move it into routine care through CDS tools that can be reused, distributed, and run in different health IT environments rather than being rebuilt from scratch for each organization. The mechanism is a U18 cooperative agreement, which generally indicates substantial federal involvement during the project, meaning awardees should expect active collaboration with AHRQ in refining aims, coordinating activities, and ensuring the work aligns with broader national priorities around interoperable CDS.
This FOA is focused on shared, interoperable CDS resources, which typically means CDS artifacts or components that can be implemented across multiple electronic health record systems and care delivery organizations with minimal rework. In practice, that emphasis points applicants toward approaches such as standardized representations of clinical knowledge, computable guidelines, interoperable CDS services, and implementation strategies that support adoption at scale. The research angle is important: the opportunity is not just about building a tool, but about studying and demonstrating better methods for disseminating evidence into practice through these interoperable resources, including the barriers, facilitators, and measurable effects on care processes and outcomes.
Eligibility is broad and spans many common domestic applicant types, including state, county, and local governments; special district governments; independent school districts; public housing authorities/Indian housing authorities; public and state-controlled institutions of higher education; private institutions of higher education; nonprofit organizations (both 501(c)(3) and non-501(c)(3)); for-profit organizations (other than small businesses); and small businesses. It also includes Native American tribal governments (federally recognized) and Native American tribal organizations (other than federally recognized tribal governments). The FOA explicitly calls out additional eligible applicant categories such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISISs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, U.S. territories or possessions, and Indian/Native American tribal governments that are not federally recognized.
At the same time, there are clear restrictions related to foreign participation. Non-domestic (non-U.S.) entities classified as foreign institutions are not eligible to apply, and non-domestic components of U.S. organizations are also not eligible to apply as applicants. However, foreign components, as defined in the HHS Grants Policy Statement, may still be involved in a limited way, specifically as members of consortia or as subcontractors, which means an otherwise eligible U.S.-based applicant could include foreign expertise or capacity through partnerships without making the foreign organization the primary applicant.
Key administrative details include the funding activity category of Health and the CFDA number 93.226. The award ceiling is listed as $500,000. The original closing date provided is January 27, 2020, and the FOA record shows a creation date of May 21, 2018. Overall, the opportunity is aimed at organizations that can combine clinical evidence expertise, informatics and interoperability know-how, and implementation research capabilities to produce CDS resources that are shareable and usable across settings, with the broader goal of making evidence-based care easier to deliver reliably at the point of care.Apply for PA 18 792
- The Agency for Health Care Research and Quality in the health sector is offering a public funding opportunity titled "Advancing Evidence into Practice through Shared, Interoperable Clinical Decision Support Resources (U18)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.226.
- This funding opportunity was created on 2018-05-21.
- Applicants must submit their applications by 2020-01-27. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $500,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQs)
What is the purpose of the Advancing Evidence into Practice through Shared, Interoperable Clinical Decision Support Resources (U18) opportunity (PA 18-792)?
This funding opportunity from the Agency for Health Care Research and Quality (AHRQ) supports research projects intended to speed up real-world adoption of proven clinical evidence by improving how clinical decision support (CDS) is created, shared, and implemented across health care settings. The goal is to move evidence (such as guidelines, best practices, and validated clinical knowledge) into routine care through CDS tools and resources that can be reused and deployed across different health IT environments without having to rebuild them from scratch for each organization.
Who is the sponsoring agency and what type of grant is this?
The sponsoring agency is AHRQ. The funding mechanism is a U18 cooperative agreement, which generally means AHRQ will have substantial involvement during the project. Awardees should expect active collaboration with AHRQ in refining aims, coordinating activities, and aligning the work with broader national priorities around interoperable CDS.
What does "shared, interoperable CDS resources" mean in this FOA?
In this FOA, "shared, interoperable CDS resources" refers to CDS artifacts or components that can be implemented across multiple electronic health record systems and care delivery organizations with minimal rework. The emphasis is on CDS that can be distributed and run in different health IT environments rather than being recreated separately for each site.
What kinds of approaches does the FOA appear to encourage for interoperability?
Based on the focus described, applicants are pointed toward approaches such as standardized representations of clinical knowledge, computable guidelines, interoperable CDS services, and implementation strategies that support adoption at scale across organizations and systems.
Is this opportunity only about building a CDS tool?
No. The FOA emphasizes a research component. It is not just about building a tool, but about studying and demonstrating better methods to disseminate evidence into practice through interoperable CDS resources. This includes examining barriers and facilitators and assessing measurable effects on care processes and outcomes.
What kinds of evidence are intended to be advanced into practice?
The FOA describes evidence broadly and includes examples such as clinical guidelines, best practices, and validated clinical knowledge that can be translated into CDS and used at the point of care.
What should applicants expect from AHRQ involvement under a U18 cooperative agreement?
A U18 cooperative agreement typically implies substantial federal involvement. As described, awardees should expect active collaboration with AHRQ in refining project aims, coordinating activities, and ensuring alignment with national priorities related to interoperable CDS.
What is the main health care impact goal of this program?
The broader goal is to make evidence-based care easier to deliver reliably at the point of care by enabling CDS resources that can be reused across settings and implemented with less reinvention and duplication.
Who is eligible to apply?
Eligibility is broad and includes many domestic applicant types, such as state, county, and local governments; special district governments; independent school districts; public housing authorities/Indian housing authorities; public and state-controlled institutions of higher education; private institutions of higher education; nonprofit organizations (501(c)(3) and non-501(c)(3)); for-profit organizations (other than small businesses); and small businesses. It also includes Native American tribal governments (federally recognized) and Native American tribal organizations (other than federally recognized tribal governments).
Are specific institution types explicitly called out as eligible?
Yes. The FOA explicitly calls out additional eligible categories including Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs); faith-based or community-based organizations; eligible federal agencies; regional organizations; U.S. territories or possessions; and Indian/Native American tribal governments that are not federally recognized.
Are non-U.S. (foreign) institutions eligible to apply as the applicant?
No. Non-domestic (non-U.S.) entities classified as foreign institutions are not eligible to apply. In addition, non-domestic components of U.S. organizations are also not eligible to apply as applicants.
Can foreign organizations participate in any way?
Yes, in a limited way. The FOA indicates that foreign components (as defined in the HHS Grants Policy Statement) may be involved as members of consortia or as subcontractors. That means an eligible U.S.-based applicant can include foreign expertise or capacity through partnerships, as long as the foreign organization is not the primary applicant.
What is the funding activity category?
The funding activity category listed is Health.
What is the CFDA number for this opportunity?
The CFDA number provided is 93.226.
What is the maximum award amount (award ceiling)?
The award ceiling is listed as $500,000.
What is the closing date listed for this FOA?
The original closing date provided is January 27, 2020.
When was the FOA record created?
The FOA record shows a creation date of May 21, 2018.
What types of organizations are a good fit for this opportunity (based on the FOA description)?
The FOA is aimed at organizations that can combine clinical evidence expertise, informatics and interoperability know-how, and implementation research capabilities to produce CDS resources that are shareable and usable across settings.
What outcomes or evaluation topics does the FOA suggest are important to study?
The FOA highlights studying barriers and facilitators to adoption and measuring effects on care processes and outcomes as part of demonstrating improved methods for disseminating evidence into practice via interoperable CDS resources.
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