Opportunity Information: Apply for RFA DP 24 031

The grant opportunity titled "Epidemiologic Cohort Study of Interstitial Cystitis" (Funding Opportunity Number RFA DP 24 031) is a CDC-funded research initiative designed to deepen public health understanding of interstitial cystitis (IC) by tracking a defined group of IC patients over time. The core aim is to conduct a longitudinal cohort study that can map how IC presents and progresses in real-world settings, including who is affected, what symptoms and clinical patterns look like across different patients, and how the condition influences overall health and daily functioning. By following individuals over time rather than relying only on one-time snapshots, the project is meant to capture changes in symptoms, care-seeking behavior, comorbidities, and quality-of-life impacts in a way that can better reflect the lived course of the condition.

A central emphasis of the NOFO is both descriptive and translational. On the descriptive side, the awardee is expected to define demographic and clinical patterns of IC, which typically means characterizing the condition across factors such as age, sex, race and ethnicity, geography, socioeconomic indicators, and other relevant population characteristics. Clinically, this involves documenting symptom profiles, diagnostic pathways, treatment experiences, and any associated health outcomes that may occur alongside IC. On the impact side, the project explicitly calls for documenting how IC affects health, which can include physical health burdens, mental health effects, functional limitations, and broader quality-of-life consequences. The goal is to produce evidence that is useful not only to researchers, but also to public health practitioners and healthcare systems trying to understand the scale and nature of IC-related burden.

Beyond generating new cohort data, the NOFO puts strong weight on translating existing scientific knowledge about IC into practical public health action. That translation component is framed as taking insights from previously funded studies and other research, then converting them into products, approaches, or strategies that can be applied by patients, providers, and public health partners. Examples of the intended direction include patient-focused strategies to improve quality of life, efforts to increase provider awareness and education, and better support for both medical management and self-management. The opportunity also highlights the importance of strengthening linkages between clinical care, community resources, and public health systems, signaling that the work is expected to bridge research findings with implementation pathways that can actually influence care and support.

Equity and disproportionate impact are also built into the focus. The NOFO specifies targeting groups disproportionately impacted by IC, which implies that the cohort study and the translation work should be attentive to disparities in burden, diagnosis, access to care, and outcomes. In practice, that could mean ensuring the cohort is designed in a way that can detect differences across populations, and that dissemination and educational outputs are tailored to address gaps affecting underserved or higher-burden communities.

This is an open competition funding announcement using a cooperative agreement mechanism, meaning recipients should expect substantial involvement from CDC compared with a standard grant. The funding instrument is a cooperative agreement, the activity category is health, and the CFDA number listed is 93.945. The award ceiling is $900,000, and the CDC anticipates making one award under this opportunity, making it a single-recipient, relatively high-stakes competition. The original application closing date was February 9, 2024, and the opportunity was created on November 15, 2023.

Eligibility is broad and includes many types of entities across government, academia, nonprofit, and private sectors. Eligible applicants include state, county, and local governments; special district governments; independent school districts; public and private institutions of higher education; federally recognized tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofits with and without 501(c)(3) status (excluding institutions of higher education in those nonprofit categories); for-profit organizations (other than small businesses); small businesses; and the opportunity is listed as unrestricted. Overall, the NOFO is structured to support a comprehensive cohort-based evidence-building effort paired with deliberate translation of findings into tools and actions that can improve patient outcomes, provider knowledge, and coordinated public health responses related to interstitial cystitis.

  • The Centers for Disease Control and Prevention - ERA in the health sector is offering a public funding opportunity titled "Epidemiologic Cohort Study of Interstitial Cystitis" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.945.
  • This funding opportunity was created on 2023-11-15.
  • Applicants must submit their applications by 2024-02-09. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $900,000.00 in funding.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Unrestricted.
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